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Local redox conditions in cells imaged via non-fluorescent transient states of NAD(P)H

The autofluorescent coenzyme nicotinamide adenine dinucleotide (NADH) and its phosphorylated form (NADPH) are major determinants of cellular redox balance. Both their fluorescence intensities and lifetimes are extensively used as label-free readouts in cellular metabolic imaging studies. Here, we in...

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Detalles Bibliográficos
Autores principales: Tornmalm, Johan, Sandberg, Elin, Rabasovic, Mihailo, Widengren, Jerker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803634/
https://www.ncbi.nlm.nih.gov/pubmed/31636326
http://dx.doi.org/10.1038/s41598-019-51526-w