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Computational/experimental evaluation of liver metastasis post hepatic injury: interactions with macrophages and transitional ECM

The complex interactions between subclinical changes to hepatic extracellular matrix (ECM) in response to injury and tumor-associated macrophage microenvironmental cues facilitating metastatic cell seeding remain poorly understood. This study implements a combined computational modeling and experime...

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Detalles Bibliográficos
Autores principales: Hudson, Shanice V., Miller, Hunter A., Mahlbacher, Grace E., Saforo, Douglas, Beverly, Levi J., Arteel, Gavin E., Frieboes, Hermann B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803648/
https://www.ncbi.nlm.nih.gov/pubmed/31636296
http://dx.doi.org/10.1038/s41598-019-51249-y