Coetaneous catalytic kinetic resolution of alkynes and azides through asymmetric triazole formation

A non-enzymatic simultaneous (coined coetaneous) kinetic resolution of a racemic alkyne and racemic azide, utilising an asymmetric CuAAC reaction is reported. The use of a CuCl (R,R)-Ph-Pybox catalyst system effects a simultaneous kinetic resolution of two racemic starting materials to give one majo...

Descripción completa

Detalles Bibliográficos
Autores principales: Brittain, William D. G., Dalling, Andrew G., Sun, Zhenquan, Duff, Cécile S. Le, Male, Louise, Buckley, Benjamin R., Fossey, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803658/
https://www.ncbi.nlm.nih.gov/pubmed/31636274
http://dx.doi.org/10.1038/s41598-019-50940-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803658/
https://www.ncbi.nlm.nih.gov/pubmed/31636274
http://dx.doi.org/10.1038/s41598-019-50940-4

Ejemplares similares