A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

Genetic studies of metabolites have identified thousands of variants, many of which are associated with downstream metabolic and obesogenic disorders. However, these studies have relied on univariate analyses, reducing power and limiting context-specific understanding. Here we aim to provide an inte...

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Detalles Bibliográficos
Autores principales: Gallois, Apolline, Mefford, Joel, Ko, Arthur, Vaysse, Amaury, Julienne, Hanna, Ala-Korpela, Mika, Laakso, Markku, Zaitlen, Noah, Pajukanta, Päivi, Aschard, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803661/
https://www.ncbi.nlm.nih.gov/pubmed/31636271
http://dx.doi.org/10.1038/s41467-019-12703-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803661/
https://www.ncbi.nlm.nih.gov/pubmed/31636271
http://dx.doi.org/10.1038/s41467-019-12703-7

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