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Microsatellite Instability assessment in Black South African Colorectal Cancer patients reveal an increased incidence of suspected Lynch syndrome

Microsatellite Instability (MSI) is a hallmark of colorectal cancer (CRC) and occurs in 15–16% of CRC. Molecular biological information of CRC in South Africa (SA) is largely unrecorded. This study was undertaken to determine the frequency of MSI, with particular reference to Lynch syndrome (LS) wit...

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Detalles Bibliográficos
Autores principales: McCabe, M., Perner, Y., Magobo, R., Magangane, P., Mirza, S., Penny, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803663/
https://www.ncbi.nlm.nih.gov/pubmed/31636305
http://dx.doi.org/10.1038/s41598-019-51316-4