A micropatterned substrate for on-surface enzymatic labelling of linearized long DNA molecules

Optical mapping of linearized DNA molecules is a promising new technology for sequence assembly and scaffolding, large structural variant detection, and diagnostics. This is currently achieved either using nanochannel confinement or by stretching single DNA molecules on a solid surface. While the fi...

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Detalles Bibliográficos
Autores principales: Varapula, Dharma, LaBouff, Eric, Raseley, Kaitlin, Uppuluri, Lahari, Ehrlich, Garth D., Noh, Moses, Xiao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803683/
https://www.ncbi.nlm.nih.gov/pubmed/31636335
http://dx.doi.org/10.1038/s41598-019-51507-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803683/
https://www.ncbi.nlm.nih.gov/pubmed/31636335
http://dx.doi.org/10.1038/s41598-019-51507-z

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