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A micropatterned substrate for on-surface enzymatic labelling of linearized long DNA molecules
Optical mapping of linearized DNA molecules is a promising new technology for sequence assembly and scaffolding, large structural variant detection, and diagnostics. This is currently achieved either using nanochannel confinement or by stretching single DNA molecules on a solid surface. While the fi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803683/ https://www.ncbi.nlm.nih.gov/pubmed/31636335 http://dx.doi.org/10.1038/s41598-019-51507-z |