Cargando…

PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production

Angiogenesis, the formation of new blood vessels from pre-existing ones, occurs in pathophysiological contexts such as wound healing, cancer, and chronic inflammatory disease. During sprouting angiogenesis, endothelial tip and stalk cells coordinately remodel their cell-cell junctions to allow colle...

Descripción completa

Detalles Bibliográficos
Autores principales: Gómez-Escudero, Jesús, Clemente, Cristina, García-Weber, Diego, Acín-Pérez, Rebeca, Millán, Jaime, Enríquez, José A., Bentley, Katie, Carmeliet, Peter, Arroyo, Alicia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803685/
https://www.ncbi.nlm.nih.gov/pubmed/31636306
http://dx.doi.org/10.1038/s41598-019-50866-x