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Iron Redox Chemistry and Implications in the Parkinson's Disease Brain

The etiology of Parkinson's disease (PD) is linked with cellular inclusions in the substantia nigra pars compacta region of the brain that are enriched in the misfolded presynaptic protein α-synuclein (αS) and death of the dopaminergic neurons. Brain iron homeostasis governs both neurotransmiss...

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Detalles Bibliográficos
Autores principales: Abeyawardhane, Dinendra L., Lucas, Heather R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803728/
https://www.ncbi.nlm.nih.gov/pubmed/31687080
http://dx.doi.org/10.1155/2019/4609702