Effects of Pyrene on Human Liver HepG2 Cells: Cytotoxicity, Oxidative Stress, and Transcriptomic Changes in Xenobiotic Metabolizing Enzymes and Inflammatory Markers with Protection Trial Using Lycopene

Pyrene is one of the major polycyclic aromatic hydrocarbons formed during heat treatment of meat and in car exhausts; however, few studies have investigated pyrene-induced adverse effects on human cell lines. This study aimed at the investigation of pyrene-induced cytotoxicity and oxidative damage i...

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Detalles Bibliográficos
Autores principales: Ma, Jin-Kui, Saad Eldin, Walaa Fathy, El-Ghareeb, Waleed Rizk, Elhelaly, Abdelazim Elsayed, Khedr, Mariam H. E., Li, Xiang, Huang, Xiao-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803749/
https://www.ncbi.nlm.nih.gov/pubmed/31687396
http://dx.doi.org/10.1155/2019/7604851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803749/
https://www.ncbi.nlm.nih.gov/pubmed/31687396
http://dx.doi.org/10.1155/2019/7604851

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