Exploring New Structural Features of the 18β-Glycyrrhetinic Acid Scaffold for the Inhibition of Anaplastic Lymphoma Kinase

Novel 18β-glycyrrhetinic acid derivatives possessing a carbamate moiety and structurally similar ester derivatives were developed and evaluated for their efficacy as antitumor inhibitors. In the cellular assays, most of the N-substituted carbamate derivatives at the C3-position exhibited potent acti...

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Detalles Bibliográficos
Autores principales: Cai, Dong, Zhang, ZhiHua, Chen, Yu, Zhang, YanYan, Sun, YuQi, Gong, YiXia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803848/
https://www.ncbi.nlm.nih.gov/pubmed/31597403
http://dx.doi.org/10.3390/molecules24193631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803848/
https://www.ncbi.nlm.nih.gov/pubmed/31597403
http://dx.doi.org/10.3390/molecules24193631

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