Structural Basis for the Regulation of PPARγ Activity by Imatinib

Imatinib is an effective anticancer drug for the treatment of leukemia. Interestingly, when an FDA-approved drug library was tested for agents that block peroxisome proliferator-activated receptor γ (PPARγ) phosphorylation at Ser245 to evaluate possibilities of antidiabetic drug repositioning, imati...

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Detalles Bibliográficos
Autores principales: Jang, Jun Young, Kim, Hyun-Jung, Han, Byung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803859/
https://www.ncbi.nlm.nih.gov/pubmed/31581474
http://dx.doi.org/10.3390/molecules24193562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803859/
https://www.ncbi.nlm.nih.gov/pubmed/31581474
http://dx.doi.org/10.3390/molecules24193562

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