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Structural Evaluation and Electrophysiological Effects of Some Kynurenic Acid Analogs

Kynurenic acid (KYNA), a metabolite of tryptophan, as an excitatory amino acid receptor antagonist is an effective neuroprotective agent in case of excitotoxicity, which is the hallmark of brain ischemia and several neurodegenerative processes. Therefore, kynurenine pathway, KYNA itself, and its der...

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Detalles Bibliográficos
Autores principales: Fehér, Evelin, Szatmári, István, Dudás, Tamás, Zalatnai, Anna, Farkas, Tamás, Lőrinczi, Bálint, Fülöp, Ferenc, Vécsei, László, Toldi, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803921/
https://www.ncbi.nlm.nih.gov/pubmed/31561643
http://dx.doi.org/10.3390/molecules24193502