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A New Class of β–Pyrrolidino-1,2,3-Triazole Derivatives as β-Adrenergic Receptor Inhibitors: Synthesis, Pharmacological, and Docking Studies

New 1,4-disubstituted β-pyrrolidino-1,2,3-triazoles were synthesized using a reusable copper-iodide-doped neutral alumina catalyst. Synthesis of diversely substituted triazoles and recyclability of CuI catalyst explains the broad scope of this protocol. The synthesized compounds were screened for th...

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Detalles Bibliográficos
Autores principales: Easwaramoorthi, Kaliyappan, A. Rajendran, Jeya, Chennakesava Rao, Kella, Balachandran, Chandrasekar, Arun, Yuvaraj, Mahalingam, Sakkarapalayam M., Arumugam, Natarajan, I. Almansour, Abdulrahman, Suresh Kumar, Raju, Al-thamili, Dhaifallah M., Aoki, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803965/
https://www.ncbi.nlm.nih.gov/pubmed/31561635
http://dx.doi.org/10.3390/molecules24193501