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Synthesis, Biological Activities and Docking Studies of Novel 4-(Arylaminomethyl)benzamide Derivatives as Potential Tyrosine Kinase Inhibitors

A number of new compounds containing the 4-(aminomethyl)benzamide fragment as a linker were designed and synthesized, and their biological activities were evaluated as potential anticancer agents. The cytotoxicity activity of the designed compounds was studied in two hematological and five solid cel...

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Detalles Bibliográficos
Autores principales: Kalinichenko, Elena, Faryna, Aliaksandr, Kondrateva, Viktoria, Vlasova, Alena, Shevchenko, Valentina, Melnik, Alla, Avdoshko, Olga, Belko, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804006/
https://www.ncbi.nlm.nih.gov/pubmed/31574962
http://dx.doi.org/10.3390/molecules24193543