Cargando…

Solid-Phase Chemical Synthesis of Stable Isotope-Labeled RNA to Aid Structure and Dynamics Studies by NMR Spectroscopy

RNA structure and dynamic studies by NMR spectroscopy suffer from chemical shift overlap and line broadening, both of which become worse as RNA size increases. Incorporation of stable isotope labels into RNA has provided several solutions to these limitations. Nevertheless, the only method to circum...

Descripción completa

Detalles Bibliográficos
Autores principales:	Becette, Owen, Olenginski, Lukasz T., Dayie, Theodore K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804060/ https://www.ncbi.nlm.nih.gov/pubmed/31557861 http://dx.doi.org/10.3390/molecules24193476

Ejemplares similares

Isotope Labels Combined with Solution NMR Spectroscopy Make Visible the Invisible Conformations of Small-to-Large RNAs
por: Dayie, Theodore K., et al.
Publicado: (2022)

Isotope-Labeled RNA Building Blocks for NMR Structure and Dynamics Studies
por: Olenginski, Lukasz T., et al.
Publicado: (2021)

Stable-Isotope-Aided NMR Spectroscopy
por: Miyanoiri, Yohei, et al.
Publicado: (2018)

Synthesis of [7-(15)N]-GTPs for RNA structure and dynamics by NMR spectroscopy
por: Taiwo, Kehinde M., et al.
Publicado: (2022)

Chemo-enzymatic synthesis of site-specific isotopically labeled nucleotides for use in NMR resonance assignment, dynamics and structural characterizations
por: Longhini, Andrew P., et al.
Publicado: (2016)

Tracking Stable Isotope Enrichment in Tree Seedlings with Solid-State NMR Spectroscopy
por: Norris, Charlotte E., et al.
Publicado: (2012)

Quantifying the effects of long-range (13)C-(13)C dipolar coupling on measured relaxation rates in RNA
por: Olenginski, Lukasz T., et al.
Publicado: (2021)

Solution NMR readily reveals distinct structural folds and interactions in doubly (13)C- and (19)F-labeled RNAs
por: Becette, Owen B., et al.
Publicado: (2020)

Quadrupolar Isotope-Correlation Spectroscopy in Solid-State NMR
por: Wolf, Tamar, et al.
Publicado: (2022)

The transient expression of recombinant proteins in plant cell packs facilitates stable isotope labelling for NMR spectroscopy
por: Opdensteinen, Patrick, et al.
Publicado: (2022)

Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy
por: Thakur, Chandar S., et al.
Publicado: (2011)

Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy
por: Thakur, Chandar S., et al.
Publicado: (2011)

Chemical Analysis of an Isotopically Labeled Molecule Using Two-Dimensional NMR Spectroscopy at 34 μT
por: Lee, Seong-Joo, et al.
Publicado: (2023)

Perspective: next generation isotope-aided methods for protein NMR spectroscopy
por: Kainosho, Masatsune, et al.
Publicado: (2018)

Isotope-Aided Methods for Biological NMR Spectroscopy: Past, Present, and Future
por: Kainosho, Masatsune, et al.
Publicado: (2017)

Simultaneous Raman and Infrared Spectroscopy of Stable Isotope Labelled Escherichia coli
por: Lima, Cassio, et al.
Publicado: (2022)

Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation
por: Rowlinson, Benjamin, et al.
Publicado: (2022)

Virtual Screening of Hepatitis B Virus Pre-Genomic RNA as a Novel Therapeutic Target
por: Olenginski, Lukasz T., et al.
Publicado: (2023)

Isotope labeling strategies for NMR studies of RNA
por: Lu, Kun, et al.
Publicado: (2009)

Selective (13)C labeling of nucleotides for large RNA NMR spectroscopy using an E. coli strain disabled in the TCA cycle
por: Thakur, Chandar S., et al.
Publicado: (2010)

Domain interactions of C-terminal Src Kinase determined through NMR spectroscopy with segmental isotope labeling
por: Liu, Dongsheng, et al.
Publicado: (2016)

Multiple conformations of SAM-II riboswitch detected with SAXS and NMR spectroscopy
por: Chen, Bin, et al.
Publicado: (2012)

Synthesis of Isotopically Labeled, Spin-Isolated Tyrosine and Phenylalanine for Protein NMR Applications
por: Young, Brandon M., et al.
Publicado: (2021)

Laser and $\beta$-NMR spectroscopy on neutron-rich magnesium isotopes
por: Kowalska, M, et al.
Publicado: (2005)

Stable Isotope Labeling with Amino acids in Nematodes
por: Larance, Mark, et al.
Publicado: (2011)

Analytical Considerations of Stable Isotope Labelling in Lipidomics
por: Triebl, Alexander, et al.
Publicado: (2018)

Solid-state (17)O NMR study of α-d-glucose: exploring new frontiers in isotopic labeling, sensitivity enhancement, and NMR crystallography
por: Shen, Jiahui, et al.
Publicado: (2022)

Hepatitis B Virus Epsilon (ε) RNA Element: Dynamic Regulator of Viral Replication and Attractive Therapeutic Target
por: Olenginski, Lukasz T., et al.
Publicado: (2023)

Monitoring Microbial Mineralization Using Reverse Stable Isotope Labeling Analysis by Mid-Infrared Laser Spectroscopy
por: Dong, Xiyang, et al.
Publicado: (2017)

Protein−Protein Interfaces Probed by Methyl Labeling and Proton‐Detected Solid‐State NMR Spectroscopy
por: Zinke, Maximilian, et al.
Publicado: (2018)

Chemical isotope labeling for quantitative proteomics
por: Tian, Xiaobo, et al.
Publicado: (2021)

Systematic NMR Analysis of Stable Isotope Labeled Metabolite Mixtures in Plant and Animal Systems: Coarse Grained Views of Metabolic Pathways
por: Chikayama, Eisuke, et al.
Publicado: (2008)

Laser spectroscopy and beta-NMR measurements of short-lived Mg isotopes
por: Kowalska, M
Publicado: (2005)

NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics
por: Lin, Penghui, et al.
Publicado: (2021)

Correction: Systematic NMR Analysis of Stable Isotope Labeled Metabolite Mixtures in Plant and Animal Systems: Coarse Grained Views of Metabolic Pathways
por: Chikayama, Eisuke, et al.
Publicado: (2009)

Correction: Systematic NMR Analysis of Stable Isotope Labeled Metabolite Mixtures in Plant and Animal Systems: Coarse Grained Views of Metabolic Pathways
por: Chikayama, Eisuke, et al.
Publicado: (2009)

RNA structure determination by solid-state NMR spectroscopy
por: Marchanka, Alexander, et al.
Publicado: (2015)

Ground-state properties of K-isotopes from laser and $\beta$-NMR spectroscopy
por: Bissell, M L, et al.
Publicado: (2011)

Measurement of nuclear moments of short-lived magnesium isotopes by $\beta$-NMR spectroscopy
por: Neyens, G, et al.
Publicado: (2003)

Ground-state properties of K-isotopes from laser and $\beta$-NMR spectroscopy
por: Neyens, G, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_oomc13it83lkrcf9u7a7uk4qet