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Benzoxaboroles—Novel Autotaxin Inhibitors

Autotaxin (ATX) is an extracellular enzyme that hydrolyses lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), which has a role in the mediation of inflammation, fibrosis and cancer. ATX is a drug target that has been the focus of many research groups during the last ten years. To date, on...

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Detalles Bibliográficos
Autores principales: Kraljić, Kristina, Jelić, Dubravko, Žiher, Dinko, Cvrtila, Adam, Dragojević, Snježana, Sinković, Verona, Mesić, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804080/
https://www.ncbi.nlm.nih.gov/pubmed/31547058
http://dx.doi.org/10.3390/molecules24193419