One-Step Synthesis of N-Succinimidyl-4-[(18)F]Fluorobenzoate ([(18)F]SFB)

Herein, we present a one-step labeling procedure of N-succinimidyl-4-[(18)F]-fluorobenzoate ([(18)F]SFB) starting from spirocyclic iodonium ylide precursors. Precursor syntheses succeeded via a simple one-pot, two-step synthesis sequence, in yields of approximately 25%. Subsequent (18)F-nucleophilic...

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Detalles Bibliográficos
Autores principales: Nymann Petersen, Ida, Madsen, Jacob, Bernard Matthijs Poulie, Christian, Kjær, Andreas, Manfred Herth, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804101/
https://www.ncbi.nlm.nih.gov/pubmed/31546683
http://dx.doi.org/10.3390/molecules24193436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804101/
https://www.ncbi.nlm.nih.gov/pubmed/31546683
http://dx.doi.org/10.3390/molecules24193436

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