Extending the Inhibition Profiles of Coumarin-Based Compounds Against Human Carbonic Anhydrases: Synthesis, Biological, and In Silico Evaluation

Carbonic anhydrases (CAs, EC 4.2.1.1) catalyze the fundamental reaction of CO(2) hydration in all living organisms and are actively involved in the regulation of a plethora of pathological and physiological conditions. A set of new coumarin/ dihydrocoumarin derivatives was here synthesized, characte...

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Detalles Bibliográficos
Autores principales: Kartsev, Victor, Geronikaki, Athina, Bua, Silvia, Nocentini, Alessio, Petrou, Anthi, Lichitsky, Boris, Frasinyuk, Mykhaylo, Leitans, Janis, Kazaks, Andris, Tars, Kaspars, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804193/
https://www.ncbi.nlm.nih.gov/pubmed/31590289
http://dx.doi.org/10.3390/molecules24193580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804193/
https://www.ncbi.nlm.nih.gov/pubmed/31590289
http://dx.doi.org/10.3390/molecules24193580

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