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Enantioselective 5-exo-Fluorocyclization of Ene-Oximes

The enantioselective 5-exo-fluorocyclization of ene-oxime compounds was demonstrated under phase-transfer catalysis. Although deprotonative fluorinations competed, the chemical yields and the ee values of the desired isoxazoline products were generally moderate to good. The absolute stereochemistry...

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Detalles Bibliográficos
Autores principales: Rouno, Taiki, Niwa, Tomoki, Nishibashi, Kousuke, Yamamoto, Nobuharu, Egami, Hiromichi, Hamashima, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804199/
https://www.ncbi.nlm.nih.gov/pubmed/31554247
http://dx.doi.org/10.3390/molecules24193464