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Enantioselective 5-exo-Fluorocyclization of Ene-Oximes
The enantioselective 5-exo-fluorocyclization of ene-oxime compounds was demonstrated under phase-transfer catalysis. Although deprotonative fluorinations competed, the chemical yields and the ee values of the desired isoxazoline products were generally moderate to good. The absolute stereochemistry...
Autores principales: | Rouno, Taiki, Niwa, Tomoki, Nishibashi, Kousuke, Yamamoto, Nobuharu, Egami, Hiromichi, Hamashima, Yoshitaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804199/ https://www.ncbi.nlm.nih.gov/pubmed/31554247 http://dx.doi.org/10.3390/molecules24193464 |
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