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Design and Synthesis of Novel 1,3-Thiazole and 2-Hydrazinyl-1,3-Thiazole Derivatives as Anti-Candida Agents: In Vitro Antifungal Screening, Molecular Docking Study, and Spectroscopic Investigation of their Binding Interaction with Bovine Serum Albumin

In the context of there being a limited number of clinically approved drugs for the treatment of Candida sp.-based infections, along with the rapid development of resistance to the existing antifungals, two novel series of 4-phenyl-1,3-thiazole and 2-hydrazinyl-4-phenyl-1,3-thiazole derivatives were...

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Detalles Bibliográficos
Autores principales: Pricopie, Andreea-Iulia, Ionuț, Ioana, Marc, Gabriel, Arseniu, Anca-Maria, Vlase, Laurian, Grozav, Adriana, Găină, Luiza Ioana, Vodnar, Dan C., Pîrnău, Adrian, Tiperciuc, Brîndușa, Oniga, Ovidiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804233/
https://www.ncbi.nlm.nih.gov/pubmed/31546673
http://dx.doi.org/10.3390/molecules24193435