Total Synthesis and Antimicrobial Evaluation of 23-Demethyleushearilide and Extensive Antimicrobial Evaluation of All Synthetic Stereoisomers of (16Z,20E)-Eushearilide and (16E,20E)-Eushearilide

A novel stereoisomer of eushearilide, 23-demethyleushearilide, was synthesized, and the structure–activity relationships of this compound along with known eushearilide stereoisomers were investigated in order to design novel lead compounds for the treatment of fungal infections. It was discovered th...

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Detalles Bibliográficos
Autores principales: Tonoi, Takayuki, Inohana, Takehiko, Sato, Teruyuki, Noda, Yuuki, Ikeda, Miyuki, Akutsu, Miku, Murata, Takatsugu, Maekawa, Yutaro, Tanaka, Anna, Seki, Rio, Ohkusu, Misako, Kamei, Katsuhiko, Ishiwada, Naruhiko, Shiina, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804234/
https://www.ncbi.nlm.nih.gov/pubmed/31546686
http://dx.doi.org/10.3390/molecules24193437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804234/
https://www.ncbi.nlm.nih.gov/pubmed/31546686
http://dx.doi.org/10.3390/molecules24193437

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