Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion

Chronic inflammation is closely associated with cancer development. One possible mechanism for inflammation-induced carcinogenesis is DNA damage caused by reactive halogen species, such as hypochlorous acid, which is released by myeloperoxidase to kill pathogens. Hypochlorous acid can attack genomic...

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Detalles Bibliográficos
Autores principales: Kou, Yi, Koag, Myong-Chul, Lee, Seongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804246/
https://www.ncbi.nlm.nih.gov/pubmed/31569643
http://dx.doi.org/10.3390/molecules24193507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804246/
https://www.ncbi.nlm.nih.gov/pubmed/31569643
http://dx.doi.org/10.3390/molecules24193507

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