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Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion
Chronic inflammation is closely associated with cancer development. One possible mechanism for inflammation-induced carcinogenesis is DNA damage caused by reactive halogen species, such as hypochlorous acid, which is released by myeloperoxidase to kill pathogens. Hypochlorous acid can attack genomic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804246/ https://www.ncbi.nlm.nih.gov/pubmed/31569643 http://dx.doi.org/10.3390/molecules24193507 |