One-Pot Metal-Free Synthesis of 3-CF(3)-1,3-Oxazinopyridines by Reaction of Pyridines with CF(3)CO-Acetylenes

The reaction of pyridines with trifluoroacetylated acetylenes was investigated. It was found that the reaction of various pyridines with two molecules of CF(3)CO-acetylenes proceeds under mild metal-free conditions. As a result, efficient stereoselective synthesis of 3-arylethynyl-3-trifluoromethyl-...

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Detalles Bibliográficos
Autores principales: Muzalevskiy, Vasiliy M., Sizova, Zoia A., Belyaeva, Kseniya V., Trofimov, Boris A., Nenajdenko, Valentine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804262/
https://www.ncbi.nlm.nih.gov/pubmed/31590462
http://dx.doi.org/10.3390/molecules24193594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804262/
https://www.ncbi.nlm.nih.gov/pubmed/31590462
http://dx.doi.org/10.3390/molecules24193594

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