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Identification and Semi-Synthesis of 3-O-Protocatechuoylceanothic Acid, a Novel and Natural GPR120 Agonist †

The identification and three step synthesis of 3-O-protocatechuoylceanothic acid, a novel and natural GPR120 agonist, is described. This ceanothane-type triterpenoid was identified from the components of Ziziphus jujuba roots and was found to be a new GPR120 agonist with a novel structure. We synthe...

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Detalles Bibliográficos
Autores principales: Lim, Changjin, Park, Jung Gyu, Kang, Kyo Bin, Suh, Young-Ger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804280/
https://www.ncbi.nlm.nih.gov/pubmed/31561452
http://dx.doi.org/10.3390/molecules24193487