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JIP1 Deficiency Protects Retinal Ganglion Cells From Apoptosis in a Rotenone-Induced Injury Model

Retinal ganglion cells (RGCs) undergo apoptosis after injury. c-Jun N-terminal kinase (JNK)-interacting protein 1 (JIP1) is a scaffold protein that is relevant to JNK activation and a key molecule known to regulate neuronal apoptosis. However, the specific role of JIP1 in the apoptosis of RGCs is cu...

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Detalles Bibliográficos
Autores principales: Liu, Wenyi, Li, Xue, Chen, Xi, Zhang, Jieqiong, Luo, Linlin, Hu, Qiumei, Zhou, Jiaxing, Yan, Jun, Lin, Sen, Ye, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804425/
https://www.ncbi.nlm.nih.gov/pubmed/31681759
http://dx.doi.org/10.3389/fcell.2019.00225