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JIP1 Deficiency Protects Retinal Ganglion Cells From Apoptosis in a Rotenone-Induced Injury Model
Retinal ganglion cells (RGCs) undergo apoptosis after injury. c-Jun N-terminal kinase (JNK)-interacting protein 1 (JIP1) is a scaffold protein that is relevant to JNK activation and a key molecule known to regulate neuronal apoptosis. However, the specific role of JIP1 in the apoptosis of RGCs is cu...
Autores principales: | Liu, Wenyi, Li, Xue, Chen, Xi, Zhang, Jieqiong, Luo, Linlin, Hu, Qiumei, Zhou, Jiaxing, Yan, Jun, Lin, Sen, Ye, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804425/ https://www.ncbi.nlm.nih.gov/pubmed/31681759 http://dx.doi.org/10.3389/fcell.2019.00225 |
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