Improvement in affinity and thermostability of a fully human antibody against interleukin-17A by yeast-display technology and CDR grafting

Monoclonal antibodies (mAbs) are widely used in many fields due to their high specificity and ability to recognize a broad range of antigens. IL-17A can induce a rapid inflammatory response both alone and synergistically with other proinflammatory cytokines. Accumulating evidence suggests that thera...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Wei, Yang, Zhaona, Lin, Heng, Liu, Ming, Zhao, Chenxi, Hou, Xueying, Hu, Zhuowei, Cui, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804450/
https://www.ncbi.nlm.nih.gov/pubmed/31649846
http://dx.doi.org/10.1016/j.apsb.2019.02.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804450/
https://www.ncbi.nlm.nih.gov/pubmed/31649846
http://dx.doi.org/10.1016/j.apsb.2019.02.007

Ejemplares similares