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OCT4B1 Promoted EMT and Regulated the Self-Renewal of CSCs in CRC: Effects Associated with the Balance of miR-8064/PLK1

Cancer stem cells (CSCs) are the main cause of tumor generation, recurrence, metastasis, and therapy failure in various malignancies including colorectal cancer (CRC). Accumulating evidence suggests that tumor cells can acquire CSC characteristics through the epithelial-mesenchymal transition (EMT)...

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Detalles Bibliográficos
Autores principales: Zhou, Jun-min, Hu, Shui-qing, Jiang, Hang, Chen, Yi-lin, Feng, Ji-hong, Chen, Zheng-quan, Wen, Kun-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804455/
https://www.ncbi.nlm.nih.gov/pubmed/31650021
http://dx.doi.org/10.1016/j.omto.2019.08.004