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Crosstalk between let-7a-5p and BCL-xL in the Initiation of Toxic Autophagy in Lung Cancer

Autophagy is essential for cellular metabolism and plays pivotal roles in carcinogenesis, while excessive autophagy induces toxicity and cell death. Our previous studies have suggested that let-7a-5p/BCL-xL might regulate autophagy in lung cancer, but the regulatory mechanism is unclear. The central...

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Detalles Bibliográficos
Autores principales: Duan, Shuyin, Li, Junxia, Tian, Jiaqi, Yin, Haoyu, Zhai, Qingfeng, Wu, Yongjun, Yao, Sanqiao, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804504/
https://www.ncbi.nlm.nih.gov/pubmed/31650027
http://dx.doi.org/10.1016/j.omto.2019.08.010