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A critical epitope in CD147 facilitates memory CD4(+) T-cell hyper-activation in rheumatoid arthritis
The abnormal activation of CD4(+)CD45RO(+) memory T (Tm) cells plays an important role in the pathogenesis of rheumatoid arthritis (RA). Previous studies have shown that CD147 participates in T-cell activation. However, it remains unclear whether CD147 is involved in abnormal Tm-cell activation in R...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804595/ https://www.ncbi.nlm.nih.gov/pubmed/29563614 http://dx.doi.org/10.1038/s41423-018-0012-4 |