A critical epitope in CD147 facilitates memory CD4(+) T-cell hyper-activation in rheumatoid arthritis

The abnormal activation of CD4(+)CD45RO(+) memory T (Tm) cells plays an important role in the pathogenesis of rheumatoid arthritis (RA). Previous studies have shown that CD147 participates in T-cell activation. However, it remains unclear whether CD147 is involved in abnormal Tm-cell activation in R...

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Detalles Bibliográficos
Autores principales: Guo, Na, Ye, Sheng, Zhang, Kui, Yu, Xiaoling, Cui, Hongyong, Yang, Xiangmin, lin, Peng, Lv, Minghua, Miao, Jinlin, Zhang, Yang, Han, Qing, Zhang, Rongguang, Chen, Zhinan, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804595/
https://www.ncbi.nlm.nih.gov/pubmed/29563614
http://dx.doi.org/10.1038/s41423-018-0012-4

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