Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the JNK/p300/p50 Signaling Pathway With Histone Acetylation

Erinacine A, which is one of the major bioactive diterpenoid compounds extracted from cultured mycelia of H. erinaceus, displays great antitumorigenic activity. However, the molecular mechanisms underlying erinacine A inducing cancer cell apoptosis in colorectal cancer (CRC) remain unclear. This stu...

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Detalles Bibliográficos
Autores principales: Lee, Ko-Chao, Lee, Kam-Fai, Tung, Shui-Yi, Huang, Wen-Shih, Lee, Li-Ya, Chen, Wan-Ping, Chen, Chin-Chu, Teng, Chih-Chuan, Shen, Chien-Heng, Hsieh, Meng-Chiao, Kuo, Hsing-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804634/
https://www.ncbi.nlm.nih.gov/pubmed/31680958
http://dx.doi.org/10.3389/fphar.2019.01174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804634/
https://www.ncbi.nlm.nih.gov/pubmed/31680958
http://dx.doi.org/10.3389/fphar.2019.01174

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