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Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the JNK/p300/p50 Signaling Pathway With Histone Acetylation
Erinacine A, which is one of the major bioactive diterpenoid compounds extracted from cultured mycelia of H. erinaceus, displays great antitumorigenic activity. However, the molecular mechanisms underlying erinacine A inducing cancer cell apoptosis in colorectal cancer (CRC) remain unclear. This stu...
Autores principales: | Lee, Ko-Chao, Lee, Kam-Fai, Tung, Shui-Yi, Huang, Wen-Shih, Lee, Li-Ya, Chen, Wan-Ping, Chen, Chin-Chu, Teng, Chih-Chuan, Shen, Chien-Heng, Hsieh, Meng-Chiao, Kuo, Hsing-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804634/ https://www.ncbi.nlm.nih.gov/pubmed/31680958 http://dx.doi.org/10.3389/fphar.2019.01174 |
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