Alleviation of paclitaxel-induced mechanical hypersensitivity and hyperalgesic priming with AMPK activators in male and female mice

AMP-activated protein kinase (AMPK) is an energy-sensing kinase that has emerged as a novel therapeutic target for pain due to its ability to inhibit mechanistic target of rapamycin (mTOR) and mitogen activated protein kinase (MAPK) signaling, two signaling pathways that are linked to pain promotion...

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Detalles Bibliográficos
Autores principales: Inyang, Kufreobong E., McDougal, Timothy A., Ramirez, Eric D., Williams, Marisa, Laumet, Geoffroy, Kavelaars, Annemieke, Heijnen, Cobi J., Burton, Michael, Dussor, Gregory, Price, Theodore J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804652/
https://www.ncbi.nlm.nih.gov/pubmed/31650090
http://dx.doi.org/10.1016/j.ynpai.2019.100037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804652/
https://www.ncbi.nlm.nih.gov/pubmed/31650090
http://dx.doi.org/10.1016/j.ynpai.2019.100037

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