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Diet‐induced DNA methylation within the hypothalamic arcuate nucleus and dysregulated leptin and insulin signaling in the pathophysiology of obesity

Obesity rates continue to rise in an unprecedented manner in what could be the most rapid population‐scale shift in human phenotype ever to occur. Increased consumption of unhealthy, calorie‐dense foods, coupled with sedentary lifestyles, is the main factor contributing to a positive energy balance...

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Detalles Bibliográficos
Autores principales: Samodien, Ebrahim, Pheiffer, Carmen, Erasmus, Melisse, Mabasa, Lawrence, Louw, Johan, Johnson, Rabia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804761/
https://www.ncbi.nlm.nih.gov/pubmed/31660128
http://dx.doi.org/10.1002/fsn3.1169