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Gene Therapy Correction of Aldehyde Dehydrogenase 2 Deficiency

Aldehyde dehydrogenase 2 (ALDH2) deficiency causes “Asian flush syndrome,” presenting as alcohol-induced facial flushing, tachycardia, nausea, and headaches. One of the most common hereditary enzyme deficiencies, it affects 35%–40% of East Asians and 8% of the world population. ALDH2 is the key enzy...

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Detalles Bibliográficos
Autores principales: Matsumura, Yuki, Stiles, Katie M., Reid, Jasmine, Frenk, Esther Z., Cronin, Samantha, Pagovich, Odelya E., Crystal, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804850/
https://www.ncbi.nlm.nih.gov/pubmed/31649957
http://dx.doi.org/10.1016/j.omtm.2019.08.004