Lentiviral Vector Purification Using Nanofiber Ion-Exchange Chromatography

Lentiviral vectors (LVs) are used in cell and gene therapies due to their ability to transduce both dividing and non-dividing cells while carrying a relatively large genetic payload and providing long-term gene expression via gene integration. Current cultivation methods produce titers of 10(5)–10(7...

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Detalles Bibliográficos
Autores principales: Ruscic, Jelena, Perry, Christopher, Mukhopadhyay, Tarit, Takeuchi, Yasu, Bracewell, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804883/
https://www.ncbi.nlm.nih.gov/pubmed/31649955
http://dx.doi.org/10.1016/j.omtm.2019.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804883/
https://www.ncbi.nlm.nih.gov/pubmed/31649955
http://dx.doi.org/10.1016/j.omtm.2019.08.007

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