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Lentiviral Vector Purification Using Nanofiber Ion-Exchange Chromatography
Lentiviral vectors (LVs) are used in cell and gene therapies due to their ability to transduce both dividing and non-dividing cells while carrying a relatively large genetic payload and providing long-term gene expression via gene integration. Current cultivation methods produce titers of 10(5)–10(7...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804883/ https://www.ncbi.nlm.nih.gov/pubmed/31649955 http://dx.doi.org/10.1016/j.omtm.2019.08.007 |