Targeting Adeno-Associated Virus Vectors for Local Delivery to Fractures and Systemic Delivery to the Skeleton

A panel of 18 recombinant adeno-associated virus (rAAV) variants, both natural and engineered, constitutively expressing Cre recombinase under the cytomegalovirus early enhancer/chicken β actin (CAG) promoter, were screened for their ability to transduce bone in Ai9 fluorescent reporter mice. Transg...

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Detalles Bibliográficos
Autores principales: Lee, Lucinda R., Peacock, Lauren, Lisowski, Leszek, Little, David G., Munns, Craig F., Schindeler, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804917/
https://www.ncbi.nlm.nih.gov/pubmed/31649959
http://dx.doi.org/10.1016/j.omtm.2019.08.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804917/
https://www.ncbi.nlm.nih.gov/pubmed/31649959
http://dx.doi.org/10.1016/j.omtm.2019.08.010

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