Adult influenza A (H3N2) with reduced susceptibility to baloxavir or peramivir cured after switching anti-influenza agents

We describe two adults with A/H3N2 influenza with (patient 1), and without (patient 2) polymerase acidic (PA) subunit I38 T substitution during the same season. Patient 1 had a reduced clinical response to baloxavir, a cap-dependent endonuclease inhibitor (CEI), but was cured by peramivir, a neurami...

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Detalles Bibliográficos
Autores principales: Seki, Masafumi, Sakai-Tagawa, Yuko, Yasuhara, Atsuhiro, Watanabe, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804930/
https://www.ncbi.nlm.nih.gov/pubmed/31692637
http://dx.doi.org/10.1016/j.idcr.2019.e00650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804930/
https://www.ncbi.nlm.nih.gov/pubmed/31692637
http://dx.doi.org/10.1016/j.idcr.2019.e00650

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