S100A4 released from highly bone-metastatic breast cancer cells plays a critical role in osteolysis
Bone destruction induced by breast cancer metastasis causes severe complications, including death, in breast cancer patients. Communication between cancer cells and skeletal cells in metastatic bone microenvironments is a principal element that drives tumor progression and osteolysis. Tumor-derived...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804941/ https://www.ncbi.nlm.nih.gov/pubmed/31667000 http://dx.doi.org/10.1038/s41413-019-0068-5 |