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2466 MicroRNA-451: A potential key player in the development of diabetic nephropathy in an insulin resistant mouse model

OBJECTIVES/SPECIFIC AIMS: MicroRNAs (miRNA) affect transcription of a number of genes involved in the development and progression of diabetic nephropathy (DN), and have become attractive therapeutic targets and biomarkers. Elevated renal gluconeogenesis, fibrosis, and albuminuria are early markers o...

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Detalles Bibliográficos
Autores principales: Fluitt, Maurice B, Li, Lijun, Shivapurkar, Narayan, Ecelbarger, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804968/
http://dx.doi.org/10.1017/cts.2018.95