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Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism

Colonocytes possess a specific carrier-mediated uptake process for the microbiota-generated thiamin (vitamin B1) pyrophosphate (TPP) that involves the TPP transporter (TPPT; product of the SLC44A4 gene). Little is known about the effect of exogenous factors (including enteric pathogens) on the colon...

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Detalles Bibliográficos
Autores principales: Anandam, Kasin Yadunandam, Sabui, Subrata, Thompson, Morgan M., Subramanian, Sreya, Said, Hamid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804999/
https://www.ncbi.nlm.nih.gov/pubmed/31639155
http://dx.doi.org/10.1371/journal.pone.0224234