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NF1-cAMP signaling dissociates cell type–specific contributions of striatal medium spiny neurons to reward valuation and motor control

The striatum plays a fundamental role in motor learning and reward-related behaviors that are synergistically shaped by populations of D1 dopamine receptor (D1R)- and D2 dopamine receptor (D2R)-expressing medium spiny neurons (MSNs). How various neurotransmitter inputs converging on common intracell...

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Detalles Bibliográficos
Autores principales: Sutton, Laurie P., Muntean, Brian S., Ostrovskaya, Olga, Zucca, Stefano, Dao, Maria, Orlandi, Cesare, Song, Chenghui, Xie, Keqiang, Martemyanov, Kirill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805008/
https://www.ncbi.nlm.nih.gov/pubmed/31600280
http://dx.doi.org/10.1371/journal.pbio.3000477