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Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

Migratory cells use distinct motility modes to navigate different microenvironments, but it is unclear whether these modes rely on the same core set of polarity components. To investigate this, we disrupted actin-related protein 2/3 (Arp2/3) and the WASP-family verprolin homologous protein (WAVE) co...

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Detalles Bibliográficos
Autores principales: Graziano, Brian R., Town, Jason P., Sitarska, Ewa, Nagy, Tamas L., Fošnarič, Miha, Penič, Samo, Iglič, Aleš, Kralj-Iglič, Veronika, Gov, Nir S., Diz-Muñoz, Alba, Weiner, Orion D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805013/
https://www.ncbi.nlm.nih.gov/pubmed/31600188
http://dx.doi.org/10.1371/journal.pbio.3000457