Inducing conformational preference of the membrane protein transporter EmrE through conservative mutations

Transporters from bacteria to humans contain inverted repeat domains thought to arise evolutionarily from the fusion of smaller membrane protein genes. Association between these domains forms the functional unit that enables transporters to adopt distinct conformations necessary for function. The sm...

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Detalles Bibliográficos
Autores principales: Leninger, Maureen, Sae Her, Ampon, Traaseth, Nathaniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805155/
https://www.ncbi.nlm.nih.gov/pubmed/31637997
http://dx.doi.org/10.7554/eLife.48909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805155/
https://www.ncbi.nlm.nih.gov/pubmed/31637997
http://dx.doi.org/10.7554/eLife.48909

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