Mitochondrial fusion is required for spermatogonial differentiation and meiosis

Differentiating cells tailor their metabolism to fulfill their specialized functions. We examined whether mitochondrial fusion is important for metabolic tailoring during spermatogenesis. Acutely after depletion of mitofusins Mfn1 and Mfn2, spermatogenesis arrests due to failure to accomplish a meta...

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Detalles Bibliográficos
Autores principales: Varuzhanyan, Grigor, Rojansky, Rebecca, Sweredoski, Michael J, Graham, Robert LJ, Hess, Sonja, Ladinsky, Mark S, Chan, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805159/
https://www.ncbi.nlm.nih.gov/pubmed/31596236
http://dx.doi.org/10.7554/eLife.51601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805159/
https://www.ncbi.nlm.nih.gov/pubmed/31596236
http://dx.doi.org/10.7554/eLife.51601

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